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Clinical trials for Sympathetic Nerve

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    18 result(s) found for: Sympathetic Nerve. Displaying page 1 of 1.
    EudraCT Number: 2009-009334-32 Sponsor Protocol Number: 07012009 Start Date*: 2009-12-28
    Sponsor Name:University medical center Utrecht
    Full Title: Effect of Statins on Sympathetic Activity in Hypertensive Patients with Chronic Kidney Disease: a Randomized trial in Hypertensive Patients with Chronic Kidney Disease
    Medical condition: atients older than 18 years old with stable chronic kidney disease and hypertension are included in this project. Patients with diabetes mellitus, patients on renal replacement therapy, patients on...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003822-80 Sponsor Protocol Number: 04/035 Start Date*: 2005-01-12
    Sponsor Name:The Leeds Teaching Hospitals NHS Trust
    Full Title: Modulation of Sympathetic Nerve Activity By Pioglitazone In Type 2 Diabetes Mellitus
    Medical condition: Type 2 diabetes mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-012449-48 Sponsor Protocol Number: ALS-8-09-A-101 Start Date*: 2009-11-09
    Sponsor Name:Air Liquide Santé International
    Full Title: „Sympathetic neural outflow during Xenon anesthesia in humans“
    Medical condition: We would like to frame the thesis, that a general, inhalative Xenon anesthesia (1 MAC) does not effect the sympathetic outflow and the sympathetic baroreflex reagibility under spontaneous breathing...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-000394-36 Sponsor Protocol Number: M17-05-LCZ-ARNI Start Date*: 2017-12-20
    Sponsor Name:Hannover Medical School
    Full Title: Influences of angiotensin-neprilysin inhibition with Sacubitril/Valsartan (ENTRESTO®) on centrally generated sympathetic activity in heart failure patients
    Medical condition: Chronic heart failure with reduced left ventricular ejection fraction (NYHA II-III)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10078289 Heart failure with reduced ejection fraction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-000411-10 Sponsor Protocol Number: 4478944789 Start Date*: Information not available in EudraCT
    Sponsor Name:BG-Kliniken Bergmannsheil, Dept. of Pain Management
    Full Title: Effects of Pregabalin on mechanical hyperalgesia - EPOM
    Medical condition: patients with pain for at least 6 months and hyperalgesia with one of the following diagnoses: peripheral nerve lesion, plexus lesion, radicular lesion, spinal lesion, polyneuropathy, postzosteric ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036105 Polyneuropathy LLT
    9.1 10036105 Polyneuropathy PT
    9.1 10036378 Postherpetic trigeminal neuralgia LLT
    9.1 10064334 Complex regional pain syndrome Type I LLT
    9.1 10064335 Complex regional pain syndrome Type II LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000628-25 Sponsor Protocol Number: 23012008 Start Date*: 2008-05-13
    Sponsor Name:UMC Utrecht
    Full Title: The effectiveness of intensive treatment on sympathetic hyperactivity. A randomized, cross-over trial in patients with chronic kidney disease and hypertension
    Medical condition: Sympathetic nerve system in hypertensive patients with chronic kidney disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005401-22 Sponsor Protocol Number: 24092007 Start Date*: 2009-02-20
    Sponsor Name:University Medical Center Utrecht
    Full Title: Effect of Aliskiren on Muscle Sympathetic Nerve Activity in hypertensive patients with chronic kidney disease
    Medical condition: Hypertension and chronic kidney disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010708-28 Sponsor Protocol Number: none02 Start Date*: 2009-07-03
    Sponsor Name:Department of Anaesthesia
    Full Title: Does the stellate ganglion block improve postoperative analgesia following upper limb trauma?
    Medical condition: We propose that the sympathetic nervous system contributes to acute pain and that a sympathetic nerve block, the stellate ganglion block, will improve postoperative pain in patients presenting for ...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002175-25 Sponsor Protocol Number: Empa2 Start Date*: 2017-09-20
    Sponsor Name:Profil Institut für Stoffwechselforschung GmbH
    Full Title: Effects on blood pressure and central sympathetic nerve traffic by SGLT2-inhibition with empagliflozin compared to hydrochlorothiazide in patients with type 2 diabetes mellitus
    Medical condition: type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000310-36 Sponsor Protocol Number: 2542 Start Date*: 2007-04-05
    Sponsor Name:Radboud University Medical Center Njmegen
    Full Title: Does statin therapy reduce sympathoexcitation in hypertension
    Medical condition: hypertension and sympathoexcitation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020782 Hypertension NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2007-006274-29 Sponsor Protocol Number: ZEMPLAR Start Date*: 2009-11-18
    Sponsor Name:Karolinska Institutet at Danderyd University Hospital
    Full Title: Sympathetic activation, microcirculation, haemostasis and inflammation in diabetic and non-diabetic kidney disease: disease modification by vitamin D receptor activation
    Medical condition: Patients with mild to moderate chronic renal failure (CRF; GFR 15-60ml/min; n=26) Patients with mild to moderate CRF and coexisting Diabetes Mellitus (n=26)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064848 Chronic kidney disease LLT
    12.0 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-003523-35 Sponsor Protocol Number: 2 Start Date*: 2011-10-28
    Sponsor Name:Department of Anaesthesia
    Full Title: A comparison of interscalene brachial plexus block combined with stellate ganglion block versus interscalene brachial plexus block for postoperative analgesia in major orthopaedic surgery of the up...
    Medical condition: We propose that an interscalene brachial plexus block combined with stellate ganglion block will give superior postoperative analgesia compared to interscalene brachial plexus block alone in majo...
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022117 - Injury, poisoning and procedural complications 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002036-14 Sponsor Protocol Number: V3.10.5.2014 Start Date*: 2014-08-08
    Sponsor Name:Lars Bo Svendsen
    Full Title: The effect of epidural anaesthesia on systemic and splanchnic hemodynamic during gastroesophageal resections, a randomized controlled trial
    Medical condition: The effect of epidural anaesthesia on systemic and splanchnic hemodynamic during gastroesophageal cancer resection
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004864 10066354 Adenocarcinoma of the gastroesophageal junction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-002256-16 Sponsor Protocol Number: 19-01SPIOMI Start Date*: 2020-01-28
    Sponsor Name:Fraunhofer Society
    Full Title: Acute and two-week effects of Spiolto® Respimat® (Tiotropium/Olodaterol) on cardiac function, the autonomic nervous system and small airway function in hyperinflated COPD subjects
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10009033 Chronic obstructive pulmonary disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-022579-68 Sponsor Protocol Number: COR-1/02 Start Date*: 2011-08-16
    Sponsor Name:Corimmun GmbH
    Full Title: COR-1, an anti-ß1 receptor antibody cyclopeptide in heart failure: a phase II, multicentre, randomised, double-blind and placebo-controlled study with parallel groups
    Medical condition: Heart Failure, Dilated Cardiomyopathy
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10056419 Dilated cardiomyopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-001581-18 Sponsor Protocol Number: SCO114520 Start Date*: 2012-03-29
    Sponsor Name:GlaxoSmithKline GmbH & Co. KG
    Full Title: Effects of bronchodilatation with salmeterol on the autonomic nervous system
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-003714-68 Sponsor Protocol Number: 1744/2017 Start Date*: 2017-11-15
    Sponsor Name:Medical University of Vienna
    Full Title: Effect of Supplemental Oxygen on Perioperative Brain Natriuretic Peptide Concentration in Cardiac Risk Patients - A prospective randomized clinical trial
    Medical condition: Evaluation of the effect of 80% versus 30% supplemental oxygen administration during major abdominal surgery on postoperative brain natriuretic peptide concentration.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10059883 Fraction of inspired oxygen PT
    20.0 100000173317 10050322 Oxygen supplementation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-004670-25 Sponsor Protocol Number: CQ-001-19 Start Date*: 2022-11-16
    Sponsor Name:Corequest sagl
    Full Title: Peritoneal Ultrafiltration in cardio Renal syndrome to prevent heart failure Exacerbation: The PURE Study
    Medical condition: Congestive Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    20.1 10007541 - Cardiac disorders 10007559 Cardiac failure congestive PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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